Current Issue : October-December Volume : 2012 Issue Number : 4 Articles : 9 Articles
Psoriasis is a chronic skin disease characterized by keratinocyte hyperproliferation and dedifferentiation, neoangiogenesis, and inflammation. T cell-mediated immunity, in which cytokines play an essential role. It is characterized by well-defined reddish (erythematous) plaques with large adherent silvery scales. The main defect in psoriasis is an increased proliferation of the skin layers due to excessive division of the cell in the basal layers of the skin. Severe itching may associate with the plaques. Dryness of the skin and silvery scaling are characterized the condition. 1% to 3% of the most population has Psoriasis. Clinically, psoriasis most frequently affects the skin of the elbow, knees, scalp, lumbosacral areas, intergluteal cleft and glans penis. In Ayurveda Psoriasis is caused by vitiation of vata and kapha dosha. There are three kinds of psoriasis called Kitibha, Ekakustha and Charmakhya....
It is presumed that Ayurvedic drugs have lesser side effects as compared to allopathic drugs. For the safety to use these plants and preparations (Oral solid dosage form, Novel drug delivery, Tropical and powder forms), the medicinal plants need to be evaluated for their toxicity. The aim of this study was to test the acute toxicity of natural materials extracted from indigenously edible fruits available in Chhattisgarh such as Diospyros melonoxylon Roxb. belonging to family Ebenaceae, commonly known as Tendu in Hindi is a small tree with rather slender stem and smooth grey bark, Buchanania lanzan spreng commonly known as Char in Hindi is a tree of 12-15 mt high, with straight trunk, belonging to family from Anacardiaceae and Manilkara zapota (Linn.) P. Royen syn., belonging to family from sapotaceae commonly known as Chiku in Hindi is a large, evergreen, forest tree more than 30 mt in height a tree belonging to family from sapotaceae. These three plants are easily available in the forests of Chhattisgarh and their various parts are used in tretment of various diseases traditionaly. The acute toxicity study was studied on Swiss mice with a dose of 2 g/Kg body weight orally. The single administration exposure of the seed powder mucilage in the form of aqueous slurry on Swiss mice was carried out and the exposure route was oral with water as a vehicle. The observations of changes in body weight, food and water intake as well as cage side observations were reported. The plants were found to be nontoxic as no mortality was recorded even at the highest dose level....
Medicinal plants role in treatment science gets justified by the history of its application by our ancestors, in almost all disease conditions. The basis of this fact; relies on the subsequent development of regionalized traditional knowledge, namely, Western medicine, Unani medicine, and Ayurvedic medicinie; originating at Mesopotamia – Egypt, Islamic block countries, and India. Cassia tora L., Casesalpiniaceae, is a wild crop and grows in most parts of India as a weed. Cassia tora L. grows in hot, wet, tropical, climates both wild and commercially. Cassia is a tonic, carminative and stimulant. Proven scientific records of possessing anthraquinones, chrysophanol, emodin, rhein, euphol, basseol, etc. supports its applicability in different disease forms. The plant has a proven pharmacological publication of having antifungal, antioxidant, ACE-inhibitor effect, effective treatment in psoriasis, antiulcer activity, antimicrobial activity, immunostimulatory effect, anticancerous, hypolipidemic, antimutagenic, hepatoprotective, antilarvicidal, and many more. Therefore, this review would focus on covering the updates of the pharmacological potential explored and stated in journals....
The present investigation was made pertaining to the effect of different concentrations of sodium chloride (NaCl) on Avicennia officinalis. Germination and growth parameters such as root length, shoot length, number of leaf, leaf area fresh weight and dry weight were analysed. Growth attributes got increased with increasing NaCl concentration up to 0.75% NaCl. Higher concentration of NaCl was inhibitory to seed germination. Thus, the optimum concentration of NaCl A. Officinalis seedlings was 0.75....
Natural products have provided important therapeutic uses in several areas of medicine. The leaves of Lagerstroemia speciosa were reported to possess good anti-diabetic activity. The present study deals with microscopical analysis, preliminary phytochemical analysis and physicochemical parameters like Ash value, Loss on drying, Extractive values which could be a useful tool to prepare a monograph for proper identification of plants. Based on the literature review, different solvents like pet ether, ethyl acetate, ethanol, methanol and water were used for extraction and these extracts were subjected to preliminary phytochemical screening which reveals the presence of tannins and terpenoids. The powdered leaves were also subjected to fluorescence analysis using different chemicals....
Work has been carried out in recent years on the beneficial effect of phenolic compounds which act as natural antioxidant and help to neutralize free radicals. In the present study we examines the potential six successive extracts (Petroleum ether, Ethyl acetate, Acetone, Methanol and Hydroalcoholic) of Syzygium cumini seeds by using standard in vitro methods and determines the phenolic content of three extracts (acetone, methanol and hydroalcoholic) on the basis of phytochemical screening. The extracts were prepared, preliminary phytochemical screening was done then three extracts were allowed for the determination of phenolic content by Folin-Ciocaltue method. The free radical scavenging activity of successive extracts was determined by 1,1-diphenyl-2-picrylhydrazyl (DPPH) assay and reducing power method. The results showed that hydroalcohol extract have highest phenolic content and free radical scavenging activity when compared with standard antioxidant ascorbic acid. Therefore study suggest that this plant could serve as a source of natural antioxidants and preservative agents with potential applications in food industries....
Medicinal herbs are significant sources for treating various diseases. Peganum harmala is used traditionally as analgesic, anti-inflammatory, abortifacient and also used for the treatment of bronchial asthma. Several phytoconstituents have been isolated and identified from different parts of the plant belonging to the category alkaloids, flavonoids and amides. Many studies have been conducted to prove its potential as anti-bacterial, anti-microbial, anthelmintic and for cytotoxic activity. The present review aims toward forming a bridge between traditional use and modern therapeutics of Peganum harmala....
Medicinal plants play a vital role to preserve our health. They are the nature’s gift to human being to have disease-free healthy life. Vernonia anthelmintica Willd. (Family- Asteraceae) is an annual plant commonly known as kalijiri in India. According to Ayurveda and Unani system of medicine, it has been used extensively for treatment of some diseases like asthma, kidney troubles, inflammatory swellings, leucoderma, worm infection and convulsion. In present investigation, the detailed pharmacognostic study of Vernonia anthelmintica Willd. fruit is carried out to lay down the standards which could be useful in future experimental studies. The study includes macroscopy, microscopy, preliminary phytochemical screening and physicochemical evaluation....
Samanea saman stem is used as laxative, antimalarial, sedative and for the treatment of stomach cancer and sore throat. The stem was evaluated for complete pharmacognostic parameters such as macroscopic study, microscopic study and powder study. Also, the powdered stem was evaluated for proximate analysis such as ash value, extractive value and quantitative microscopy. Transverse section of stem of Samanea saman showed presence of epidermis, hypodermis, endodermis, pericyclic fibres, phloem, xylem and pith. Powder study of stem of Samanea saman showed presence of pericyclic fibres, pitted xylem fibres, trimular shaped starch, and covering trichomes. Qualitative chemical examination of various successive extracts of stem showed the presence of carbohydrates, phytosterols, saponin, phenolic compounds and tannin. Phytochemical study showed the presences of phenolics and tannins in Samanea saman methanolic extract (SSME). The methanolic extract of Samanea saman (SSME) have higher IC50 value compared to Ascorbic acid (Std.) which indicates that extract scavenge free radicals like NO, Superoxide, DPPH in higher concentration so concentration required to produce significant antioxidant activity is high. But extract showing significant antioxidant activity for superoxide free radicals which might be beneficial in improvement of pathological condition like liver injury....
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